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  • BMI1抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW16820
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:BMI1抗原(重組蛋白)

英文名稱: BMI1 Antigen (Recombinant Protein)

別      名: PCGF4; RNF51; FLVI2/BMI1

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to N terminal 250 amino acids of human BMI1


技術(shù)規(guī)格:

Full name:

BMI1 polycomb ring finger oncogene

Synonyms:

PCGF4; RNF51; FLVI2/BMI1

Swissprot:

P35226

Gene Accession:

BC011652

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.