中文名稱: BPI抗原(重組蛋白)
英文名稱: BPI Antigen (Recombinant Protein)
別 名: rBPI; BPIFD1
儲 存: 冷凍(-20℃)
相關類別: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human BPI |
Full name: |
bactericidal/permeability-increasing protein |
Synonyms: |
rBPI; BPIFD1 |
Swissprot: |
P17213 |
Gene Accession: |
BC040955 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has bactericidal activity on gram-negative organisms. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |