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  • MMP12抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16848
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱： MMP12抗原（重組蛋白）

英文名稱： MMP12 Antigen (Recombinant Protein)

別       名： ME; HME; MME; MMP-12

儲       存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 216-470 amino acids of human MMP12

技術(shù)規(guī)格

Full name:

matrix metallopeptidase 12 (macrophage elastase)

Synonyms:

ME; HME; MME; MMP-12

Swissprot:

P39900

Gene Accession:

BC112301

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin.