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  • MSH3抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16864
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: MSH3抗原(重組蛋白)

英文名稱: MSH3 Antigen (Recombinant Protein)

別       名: DUP; FAP4; MRP1

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a C terminal 300 amino acids of human MSH3

技術(shù)規(guī)格

Full name:

mutS homolog 3

Synonyms:

DUP; FAP4; MRP1

Swissprot:

P20585

Gene Accession:

BC130436

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.