購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：CBR1抗原（重組蛋白）
英文名稱： CBR1 Antigen (Recombinant Protein)
別 名： CBR; hCBR1; SDR21C1
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 2-277 amino acids of human CBR1 |
技術(shù)規(guī)格：
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Full name: |
carbonyl reductase 1 |
|
Synonyms: |
CBR; hCBR1; SDR21C1 |
|
Swissprot: |
P16152 |
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Gene Accession: |
BC002511 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. |
