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細(xì)胞系

細(xì)胞庫

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菌株

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科研抗體

CERK抗原（重組蛋白）

規(guī)格：

數(shù)量：

購買數(shù)量

價格：￥

中文名稱：CERK抗原（重組蛋白）

英文名稱： CERK Antigen (Recombinant Protein)

別名： LK4; hCERK; dA59H18.2; dA59H18.3

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 128-278 amino acids of human CERK

技術(shù)規(guī)格：

Full name:	ceramide kinase
Synonyms:	LK4; hCERK; dA59H18.2; dA59H18.3
Swissprot:	Q8TCT0
Gene Accession:	BC126940
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

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