兔抗MAP3K11多克隆抗體

Background:

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.

Applications:

ELISA, WB, IHC

Name of antibody:

MAP3K11

Immunogen:

Synthetic peptide of human MAP3K11

Synonyms:

MLK3; PTK1; SPRK; MLK-3; MEKK11

SwissProt:

Q16584

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human gastric cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

93 kDa

WB Positive control:

LO2 and PC-3 cell lysates

WB Recommended dilution:

500-2000

Full name:

mitogen-activated protein kinase kinase kinase 11