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  • DNMT3A抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17107
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:90
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中文名稱:DNMT3A抗原(重組蛋白)

英文名稱: DNMT3A Antigen (Recombinant Protein)

別      名: DNMT3A2; M.HsaIIIA

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to C terminal 300 amino acids of human DNMT3A


技術(shù)規(guī)格:

Full name:

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonyms:

DNMT3A2; M.HsaIIIA

Swissprot:

Q9Y6K1

Gene Accession:

BC043617

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.