購物車
幫助
021-54845833/15800441009
中文名稱： FTO抗原（重組蛋白）
英文名稱： FTO Antigen (Recombinant Protein)
別 名： ALKBH9
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 456-505 amino acids of human FTO |
|
Full name: |
fat mass and obesity associated |
|
Synonyms: |
ALKBH9 |
|
Swissprot: |
Q9C0B1 |
|
Gene Accession: |
BC003583 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |
