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  • ICAM1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17441
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：90
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中文名稱：ICAM1抗原（重組蛋白）

英文名稱： ICAM1 Antigen (Recombinant Protein)

別      名： BB2; CD54; P3.58

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to a region derived from 28-328 amino acids of human ICAM1


技術(shù)規(guī)格：

Full name:

intercellular adhesion molecule 1

Synonyms:

BB2; CD54; P3.58

Swissprot:

P05362

Gene Accession:

BC015969

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.