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  • KLC1抗原(重組蛋白)

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    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17473
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱:KLC1抗原(重組蛋白)

英文名稱: KLC1 Antigen (Recombinant Protein)

別      名: KLC; KNS2; KNS2A

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to N terminal 213 amino acids of human KLC1


技術(shù)規(guī)格:

Full name:

kinesin light chain 1

Synonyms:

KLC; KNS2; KNS2A

Swissprot:

Q07866

Gene Accession:

BC008881

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined.