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  • USP2抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17837
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:90
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中文名稱USP2抗原(重組蛋白)

英文名稱: USP2 Antigen (Recombinant Protein)

別     名: USP9; UBP41

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概  述:

Fusion protein corresponding to a region derived from C terminal 250 amino acids of human USP2


技術(shù)規(guī)格:

Full name:

ubiquitin specific peptidase 2

Synonyms:

USP9; UBP41

Swissprot:

O75604

Gene Accession:

BC002854

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.