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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17874
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱(chēng): 兔抗MAPT (Phospho-Ser404)多克隆抗體


英文名稱(chēng): Anti-MAPT (Phospho-Ser404) rabbit polyclonal antibody


別       名: TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17


相關(guān)類(lèi)別: 一抗


儲(chǔ)      存: 冷凍(-20℃) 避光


宿      主: Rabbit


抗      原: MAPT (Phospho-Ser404)


反應(yīng)種屬: Human, Mouse, Rat


標(biāo)  記  物: Unconjugate


克隆類(lèi)型: rabbit polyclonal


技術(shù)規(guī)格


Background:

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Applications:

WB, IHC, IF

Name of antibody:

MAPT (Phospho-Ser404)

Immunogen:

Synthetic peptide of human MAPT (Phospho-Ser404)

Full name:

microtubule-associated protein tau (Phospho-Ser404)

Synonyms:

TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17

SwissProt:

P10636

IHC positive control:

Rat hippocampal regionfrom a model with Alzheimer’s Disease

IHC Recommend dilution:

50-100

WB Predicted band size:

48 kDa; 62 kDa; 78 kDa

WB Positive control:

Mouse Brain tissue

WB Recommended dilution:

500-1000

IF Positive control:

Hela cells

IF Recommended dilution

100-200