中文名稱:IL18R1抗原(重組蛋白)
英文名稱: IL18R1 Antigen (Recombinant Protein)
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概述
Fusion protein corresponding to a region derived from 75-329 amino acids of human IL18R1 |
Full name: |
interleukin 18 receptor 1 |
Synonyms: |
CD218a; IL18RA; IL1RRP; CDw218a; IL-1Rrp |
Swissprot: |
Q13478 |
Gene Accession: |
BC069575 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |