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  • PBXIP1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17956
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱：PBXIP1抗原（重組蛋白）

英文名稱： PBXIP1 Antigen (Recombinant Protein)

別       名： PBX homeobox interacting protein 1; HPIP

儲       存： 冷凍（-20℃）
相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 532-731 amino acids of human PBXIP1

技術(shù)規(guī)格

Full name:

PBX homeobox interacting protein 1

Synonyms:

HPIP

Swissprot:

Q96AQ6

Gene Accession:

BC016852

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.