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  • IMPDH2 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17973
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:  IMPDH2 抗原(重組蛋白)

英文名稱 IMPDH2 Antigen (Recombinant Protein)

儲      存: 冷凍(-20℃)

別      名: IMP (inosine 5'-monophosphate) dehydrogenase 2; IMPD2; IMPDH-II

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 114-237 amino acids of human IMPDH2


技術(shù)規(guī)格


Full name:

IMP (inosine 5'-monophosphate) dehydrogenase 2

Synonyms:

IMPD2; IMPDH-II

Swissprot:

P12268

Gene Accession:

BC006124

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.