購物車
幫助
021-54845833/15800441009
中文名稱：ITGA4抗原（重組蛋白）
英文名稱： ITGA4 Antigen (Recombinant Protein)
別 名： IA4; CD49D
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 756-1032 amino acids of human ITGA4 |
|
Full name: |
integrin subunit alpha 4 |
|
Synonyms: |
IA4; CD49D |
|
Swissprot: |
P13612 |
|
Gene Accession: |
BC080190 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
