ELISA試劑盒

PCR試劑盒

生化試劑盒

細胞系

細胞庫

基礎培養(yǎng)基

完全培養(yǎng)基

原代細胞

細胞專用培養(yǎng)基

菌株

生化試劑

病理染色液

科研抗體

PLEKHG6抗原（重組蛋白）

規(guī)格：

數(shù)量：

購買數(shù)量

價格：￥

中文名稱： PLEKHG6抗原（重組蛋白）

英文名稱： PLEKHG6 Antigen (Recombinant Protein)

別名： pleckstrin homology domain containing, family G (with RhoGef domain) member 6; MyoGEF

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 161-353 amino acids of human PLEKHG6

技術規(guī)格

Full name:	pleckstrin homology domain containing, family G (with RhoGef domain) member 6
Synonyms:	MyoGEF
Swissprot:	Q3KR16
Gene Accession:	BC105961
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

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