兔抗AMACR多克隆抗體

Background:

This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Applications:

ELISA, WB, IHC

Name of antibody:

AMACR

Immunogen:

Fusion protein of human AMACR

Full name:

alpha-methylacyl-CoA racemase

Synonyms：

RM; RACE; CBAS4; AMACRD

SwissProt:

Q9UHK6

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

42 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

200-1000