中文名稱:PCBD1抗原(重組蛋白)
英文名稱: PCBD1 Antigen (Recombinant Protein)
別 名: PCD; PHS; DCOH; PCBD
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-104 amino acids of human PCBD1 |
Full name: |
pterin-4 alpha-carbinolamine dehydratase 1 |
Synonyms: |
PCD; PHS; DCOH; PCBD |
Swissprot: |
P61457 |
Gene Accession: |
BC006324 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants. |