兔抗AMIGO2多克隆抗體

Background:

The amphoterin-induced gene and ORF (AMIGO) family of proteins consists of AMIGO-1, AMIGO-2 and AMIGO-3. All three members are single pass type I membrane proteins that contain several leucine-rich repeats, one IgG domain, and a transmembrane domain. The AMIGO proteins are specifically expressed on fiber tracts of neuronal tissues and participate in their formation. The AMIGO proteins can form complexes with each other, but can also bind itself. AMIGO-1, also designated Alivin-2, promotes growth and fasciculation of neurites and plays a role in myelination and fasciculation of developing neural axons. In cerebellar neurons, AMIGO-2 (Alivin-1) is crucial for depolarization-dependent survival. Similar to AMIGO-1 and AMIGO-2, AMIGO-3 (Alivin-3) plays a role in homophilic and/or heterophilic cell-cell interaction and signal transduction

Applications:

ELISA, WB, IHC

Name of antibody:

AMIGO2

Immunogen:

Fusion protein of human AMIGO2

Full name:

adhesion molecule with Ig-like domain 2

Synonyms：

ALI1; DEGA; AMIGO-2

SwissProt:

Q86SJ2

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer and human breast cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

58 kDa

WB Positive control:

SP20 cells and mouse heart tissue

WB Recommended dilution:

500-2000