SETDB1抗原（重組蛋白）

Full name:

SET domain bifurcated 1

Synonyms:

ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4

Swissprot:

Q15047

Gene Accession:

BC009362

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.