中文名稱:BEX2抗原(重組蛋白)
英文名稱: BEX2 Antigen (Recombinant Protein)
別 名: BEX1; DJ79P11.1
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 1-128 amino acids of human BEX2 |
Full name: |
brain expressed X-linked 2 |
Synonyms: |
BEX1; DJ79P11.1 |
Swissprot: |
Q9BXY8 |
Gene Accession: |
BC015522 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. |