兔抗MMP15多克隆抗體

Background:

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted.

Applications:

ELISA, WB

Name of antibody:

MMP15

Immunogen:

Fusion protein of human MMP15

Full name:

matrix metallopeptidase 15 (membrane-inserted)

Synonyms：

MTMMP2, SMCP-2, MT2-MMP

SwissProt:

P51511

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

76 kDa

WB Positive control:

Mouse stomach, heart and liver tissue, HT-29 cells

WB Recommended dilution:

500-2000