兔抗FGF4多克隆抗體

Background:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Applications:

ELISA, IHC

Name of antibody:

FGF4

Immunogen:

Synthetic peptide of human FGF4

Full name:

fibroblast growth factor 4

Synonyms：

HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4

SwissProt:

P08620

ELISA Recommended dilution:

1000-10000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

50-150