Background: |
This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Applications: |
ELISA, IHC |
Name of antibody: |
FLCN |
Immunogen: |
Fusion protein of human FLCN |
Full name: |
folliculin |
Synonyms: |
BHD; FLCL |
SwissProt: |
Q8NFG4 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human thyroid cancer and Human liver cancer |
IHC Recommend dilution: |
100-300 |