兔抗SETDB1多克隆抗體

Background:

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Applications:

ELISA, IHC

Name of antibody:

SETDB1

Immunogen:

Fusion protein of human SETDB1

Full name:

SET domain bifurcated 1

Synonyms:

ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4

SwissProt:

Q15047

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancerHuman thyroid cancer

IHC Recommend dilution:

50-300