兔抗SGCA多克隆抗體

Background:

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

SGCA

Immunogen:

Fusion protein of human SGCA

Full name:

sarcoglycan alpha

Synonyms:

ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin

SwissProt:

Q16586

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human lung cancer

IHC Recommend dilution:

25-100