兔抗PFN2多克隆抗體

Background:

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Applications:

ELISA, WB, IHC

Name of antibody:

PFN2

Immunogen:

Synthetic peptide of human PFN2

Full name:

Profilin 2

Synonyms：

PFL, D3S1319E

SwissProt:

P35080

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human brain and Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

15 kDa

WB Positive control:

Human fetal brain tissue

WB Recommended dilution:

500-2000