兔抗PLCG1(Ab-771)多克隆抗體

Background:

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.

Applications:

WB, IHC

Name of antibody:

PLCG1(Ab-771)

Immunogen:

Synthesized non-phosphopeptide derived from human PLCG1 around the phosphorylation site of tyrosine 771 (P-D-Y-G-A).

Full name:

phospholipase C, gamma 1

Synonyms：

phospholipase C, gamma 1

SwissProt:

P19174

IHC positive control:

Human breast carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

149 kDa

WB Positive control:

COS7 cells treated with EGF (200ng/ml, 30min) lysate

WB Recommended dilution:

500-3000