中文名稱: 兔抗PRKAR2B(Phospho-Ser113) 多克隆抗體
英文名稱: Anti-PRKAR2B(Phospho-Ser113) rabbit polyclonal antibody
別 名: PRKAR2; RII-BETA
相關類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: PRKAR2B(Phospho-Ser113)
反應種屬: Human Mouse Rat
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術規(guī)格
Background: |
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. |
Applications: |
WB |
Name of antibody: |
PRKAR2B(Phospho-Ser113) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine113(R-R-A(p)-S-V) derived from Human PKA-R2β. |
Full name: |
protein kinase, cAMP-dependent, regulatory, type II, beta |
Synonyms: |
PRKAR2; RII-BETA |
SwissProt: |
P31323 |
WB Predicted band size: |
46 kDa |
WB Positive control: |
COS7 cells lysates treated with PMA |
WB Recommended dilution: |
500-1000 |