中文名稱: 兔抗PSMC2多克隆抗體
英文名稱: Anti-PSMC2 rabbit polyclonal antibody
別 名: S7; MSS1; Nbla10058
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: PSMC2
反應(yīng)種屬: Human, Mouse, Rat
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
PSMC2 |
Immunogen: |
Fusion protein of human PSMC2 |
Full name: |
proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
Synonyms: |
S7; MSS1; Nbla10058 |
SwissProt: |
P35998 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and human breast cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
49 kDa |
WB Positive control: |
231 cells |
WB Recommended dilution: |
500-2000 |