歡迎來到上海通蔚!

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 一抗 > 兔抗SPAG8多克隆抗體
  • 兔抗SPAG8多克隆抗體

    規(guī)格:
    數(shù)量:

    購買數(shù)量

    價格:
    • 品牌 : 通蔚生物
    • 目錄號 : TW22403
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:75
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關(guān)產(chǎn)品



中文名稱:兔抗SPAG8多克隆抗體

英文名稱: Anti-SPAG8 rabbit polyclonal antibody

別      名: SMP1, BS-84, HSD-1, SPAG3, hSMP-1

抗      原: SPAG8

儲      存: 冷凍(-20℃)

宿      主: Rabbit

相關(guān)類別: 一抗

反應(yīng)種屬: Human

標  記 物: Unconjugate

克隆類型: rabbit polyclonal

技術(shù)規(guī)格

Background:

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis. This protein may also play a role in spermatogenesis by regulating microtubule formation and cell division. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Applications:

ELISA, IHC

Name of antibody:

SPAG8

Immunogen:

Fusion protein of human SPAG8

Full name:

sperm associated antigen 8

Synonyms:

SMP1, BS-84, HSD-1, SPAG3, hSMP-1

SwissProt:

Q99932

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100