兔抗ATXN1多克隆抗體

Background:

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.

Applications:

ELISA, IHC

Name of antibody:

ATXN1

Immunogen:

Fusion protein of human ATXN1

Full name:

ataxin 1

Synonyms：

ATX1; SCA1; D6S504E

SwissProt:

P54253

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

50-200