兔抗BCL3多克隆抗體

Background:

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.

Applications:

ELISA, IHC

Name of antibody:

BCL3

Immunogen:

Synthetic peptide of human BCL3

Full name:

B-cell CLL/lymphoma 3

Synonyms:

BCL4; D19S37

SwissProt:

P20749

IHC positive control:

Human gastric cancer and human thyroid cancer

IHC Recommend dilution:

25-100