兔抗CA11多克隆抗體

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.

Applications:

ELISA, IHC

Name of antibody:

CA11

Immunogen:

Fusion protein of human CA11

Full name:

carbonic anhydrase 11

Synonyms:

CARPX1

SwissProt:

O75493

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

30-150