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  • DECR2 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4394
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱:DECR2 抗原(重組蛋白)

英文名稱:DECR2 Antigen (Recombinant Protein)

別     名: 2,4-dienoyl CoA reductase 2, peroxisomal; PDCR; SDR17C1

相關(guān)類別:抗原

儲     存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 49-292 amino acids of human DECR2

技術(shù)規(guī)格

Full name:

2,4-dienoyl CoA reductase 2, peroxisomal

Synonyms:

PDCR; SDR17C1

Swissprot:

Q9NUI1

Gene Accession:

BC011968

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

DECR2 (2,4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2,4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2,4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA and short and medium chain 2,4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.