中文名稱:兔抗CCDC88A多克隆抗體
英文名稱: Anti-CCDC88A rabbit polyclonal antibody
別 名: APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
抗 原: CCDC88A
宿 主: Rabbit
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
CCDC88A |
Immunogen: |
Synthetic peptide of human CCDC88A |
Full name: |
coiled-coil domain containing 88A |
Synonyms: |
APE; GIV; GRDN; HkRP1; GIRDIN; KIAA1212 |
SwissProt: |
Q3V6T2 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human cervical cancer and Human colon cancer |
IHC Recommend dilution: |
50-200 |