兔抗CCNF多克隆抗體

Background:

This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified.

Applications:

ELISA, WB, IHC

Name of antibody:

CCNF

Immunogen:

Synthetic peptide of human CCNF

Full name:

cyclin F

Synonyms:

FBX1; FBXO1

SwissProt:

P41002

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

88 kDa

WB Positive control:

293T cell lysate

WB Recommended dilution:

500-2000