兔抗XRCC3多克隆抗體

Background:

This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Applications:

WB, IHC

Name of antibody:

XRCC3

Immunogen:

Synthesized peptide derived from Internal of human XRCC3.

Full name:

X-ray repair complementing defective repair in Chinese hamster cells 3

Synonyms：

CMM6

SwissProt:

O43542

IHC positive control:

Human lung carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

38 kDa

WB Positive control:

HepG2 cells treated with Adriamycin (0.5uM, 5hours) lysate

WB Recommended dilution:

500-3000