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  • TCIM 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW5339
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
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中文名稱：TCIM 抗原（重組蛋白）

英文名稱：TCIM Antigen (Recombinant Protein)

別     名： transcriptional and immune response regulator; TC1; TC-1; C8orf4

儲(chǔ)     存： 冷凍（-20℃）

相關(guān)類別：抗原

概     述

Fusion protein corresponding to a region derived from 1-106 amino acids of human TCIM

技術(shù)規(guī)格

Full name:

transcriptional and immune response regulator

Synonyms:

TC1; TC-1; C8orf4

Swissprot:

Q9NR00

Gene Accession:

BC020623

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]