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  • TUBGCP4 抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW5844
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
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中文名稱： TUBGCP4 抗原（重組蛋白）

英文名稱： TUBGCP4 Antigen (Recombinant Protein)

別     名：  tubulin gamma complex associated protein 4; 76P; GCP4; GCP-4; Grip76; MCCRP3

儲    存：   冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 468-667 amino acids of human TUBGCP4

技術(shù)規(guī)格

Full name:

tubulin gamma complex associated protein 4

Synonyms:

76P; GCP4; GCP-4; Grip76; MCCRP3

Swissprot:

Q9UGJ1

Gene Accession:

BC009870

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.