中文名稱: UBE2R2 抗原(重組蛋白)
英文名稱: UBE2R2 Antigen (Recombinant Protein)
別 名: ubiquitin conjugating enzyme E2 R2; UBC3B; CDC34B; E2-CDC34B
相關類別:抗原
儲 存: 冷凍(-20℃)
概 述
Full name: |
ubiquitin conjugating enzyme E2 R2 |
Synonyms: |
UBC3B; CDC34B; E2-CDC34B |
Swissprot: |
Q712K3 |
Gene Accession: |
BC004862 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. |