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  • USP5 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW6334
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存:20
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中文名稱: USP5 抗原(重組蛋白)

英文名稱: USP5 Antigen (Recombinant Protein)

別     名: ubiquitin specific peptidase 5 (isopeptidase T); ISOT

儲(chǔ)     存: 冷凍(-20℃)

相關(guān)類別:抗原

概     述

Fusion protein corresponding to C terminal 200 amino acids of human USP5

技術(shù)規(guī)格

Full name:

ubiquitin specific peptidase 5 (isopeptidase T)

Synonyms:

ISOT

Swissprot:

P45974

Gene Accession:

BC004889

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).