歡迎來到上海通蔚！

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > VSIG8 抗原（重組蛋白）

產(chǎn)品中心

  • VSIG8 抗原（重組蛋白）

    規(guī)格：
    數(shù)量：

    購買數(shù)量

    價格：￥
    • 品牌 : 通蔚生物
    • 目錄號 : TW6476
    • 應用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：20
  • 商品詳情
  • 參考文獻
  • 說明書下載
  • 商品評論0
  • 相關(guān)產(chǎn)品

中文名稱： VSIG8 抗原（重組蛋白）

英文名稱： VSIG8 Antigen (Recombinant Protein)

儲     存： 冷凍（-20℃）

別     名： V-set and immunoglobulin domain containing 8

相關(guān)類別：抗原

概     述

Fusion protein corresponding to a region derived from 215-414 amino acids of human VSIG8

技術(shù)規(guī)格

Full name:

V-set and immunoglobulin domain containing 8

Swissprot:

P0DPA2

Gene Accession:

BC132893

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

VSIG8 (V-set and immunoglobulin domain-containing protein 8), also known as C1orf204, is a 414 amino acid single-pass type I membrane protein that contains two Ig-like V-type (immunoglobulin-like) domains. VSIG8 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 1q23.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. The rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia.