中文名稱(chēng): XPNPEP3 抗原(重組蛋白)
英文名稱(chēng): XPNPEP3 Antigen (Recombinant Protein)
別 名: X-prolyl aminopeptidase 3; APP3; ICP55; NPHPL1
儲(chǔ) 存: 冷凍(-20℃)
相關(guān)類(lèi)別:抗原
概 述
Full name: |
X-prolyl aminopeptidase 3 |
Synonyms: |
APP3; ICP55; NPHPL1 |
Swissprot: |
Q9NQH7 |
Gene Accession: |
BC001681 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known. |