中文名稱:小鼠抗FSCN1單克隆抗體
Background: |
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
Applications: |
ELISA, WB |
Name of antibody: |
FSCN1 |
Immunogen: |
Fusion protein of human FSCN1 |
Full name: |
fascin actin-bundling protein 1 |
Synonyms: |
HSN; SNL; p55; FAN1 |
SwissProt: |
Q16658 |
WB Predicted band size: |
55 kDa |
WB Positive control: |
HEPG2 whole cell lysate |
WB Recommended dilution: |
500-2000 |