小鼠抗HNRNPH1單克隆抗體

Background:

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described

Applications:

WB, IHC

Name of antibody:

HNRNPH1

Immunogen:

Fusion protein of human HNRNPH1

Full name:

heterogeneous nuclear ribonucleoprotein H1

Synonyms:

HNRPH; HNRPH1; hnRNPH

SwissProt:

P31943

IHC positive control:

Human breast tissue and Human pancreas tissue; Human prostate tissue and Human spleen tissue

IHC Recommend dilution:

200-500

WB Predicted band size:

49 KD

WB Positive control:

A431, Hela, HepG2, Raji, Jurkat, K562, U251, HUH7 cell lysates

WB Recommended dilution:

500-2000