小鼠抗LOX單克隆抗體

Background:

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Applications:

WB, IHC, IF, FC

Name of antibody:

LOX

Immunogen:

Fusion protein of human LOX

Full name:

lysyl oxidase (LOX), transcript variant 1

Synonyms:

MGC105112

SwissProt:

P28300

IHC positive control:

human colon tissue

IHC Recommend dilution:

10-50

WB Predicted band size:

47 kDa

WB Positive control:

MDCK, PC12 cell lysates

WB Recommended dilution:

500-2000