小鼠抗MAGEB1單克隆抗體

Background:

This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. This gene and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008].

Applications:

WB, IHC

Name of antibody:

MAGEB1

Immunogen:

Fusion protein of human MAGEB1

Full name:

melanoma antigen family B1 (MAGEB1), transcript variant 2

Synonyms:

CT3.1; DAM10; MAGE-Xp; MAGEL1

SwissProt:

P43366

IHC positive control:

carcinoma of human bladder tissue

IHC Recommend dilution:

25-100

WB Predicted band size:

39 kDa

WB Positive control:

HepG2, Hela, SVT2, A549, Jurkat, MDCK cell lysates

WB Recommended dilution:

1000-5000